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Oxycodone, from its chemical name dihydrooxycodeinone, belongs to the family of opioid painkillers . It is a very powerful analgesic, derived from the synthesis of an alkaloid naturally present in opium: thebaine. It is a surprising drug, more potent than codeine and with a significant risk of dependence. In its raw form, oxycodone is an odorless white powder.
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Oxycodone effects
Oxycodone reduces pain by acting on the central nervous system. Its effects include analgesics, anxiolytics, antihistamines, and sedatives. Because oxycodone is exclusively an agonist at opioid receptors, the analgesic effect is dose-dependent, with no set maximum dose, as long as adverse effects are controlled.
Buying oxycodone without a prescription can also affect the hypothalamic-pituitary-supremacist (or gonadic) axis, leading to changes such as increased blood prolactin and decreased cortisol and testosterone. These hormonal changes can manifest as various symptoms.
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Oxycodone is an opioid painkiller. It is an agonist of the kappa, MU, and delta opioid receptors in the brain, spinal cord, and peripheral organs. By repairing itself on these receptors, it activates their therapeutic effects.
Oxycodone for Sale | When Should You Take Oxycodone?
Oxycodone for sale is indicated for severe pain that cannot be relieved by lower-level analgesics, such as cancer pain.
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Oxycodone pris and morphine have a similar mechanism of action. On the other hand, when administered orally, oxycodone ‘s effect on pain is 1.5 to 2 times more potent than that of morphine (depending on the morphine dose being compared). However, this difference is not found with the injectable route, where oxycodone’s pain effectiveness is comparable to that of morphine. Furthermore, oxycodone has the advantage of being effective against neuropathic pain.
Side effects experiences
- constipation, which needs to be treated.
- Drowsiness, nausea and vomiting, which subside after a while.
- Vertiginous sensations, itching, headache.
- Decrease in appetite.
- Anxiety, confusional state, depression, insomnia, nervousness, thought disturbances, nightmares, especially in the elderly, with possible hallucinations (abnormal perception of an object that does not exist in reality).
- tremors, increased intracranial pressure resulting in headache or even vomiting.
- Difficulty breathing (dyspnea).
- Abdominal pain, diarrhea, dry mouth, stomach pain (dyspepsia).
- Rash, excessive sweating (hyperhidrosis).
- asthenia.
- Allergic reaction (hypersensitivity).
- Dehydration.
- Agitation, rapid and significant change in mood.
- Memory disturbances (amnesis), convulsions, excessive muscle tone (hypertonia), decreased sensitivity to touch (hypoesthesia), involuntary muscle contractions, language disturbances, discomfort (syncope), tingling or numbness in the limbs (paraesthesia), taste disturbances (dygaguea).
- Vision disorders, narrowing of the pupil (miosis).
- dizziness.
- palpitations (in case of withdrawal syndrome).
- Long-term use of oxycodone during pregnancy can cause weaning symptoms in newborns, potentially jeopardizing their vital prognosis. Symptoms to monitor for in newborns include irritability, hyperactivity, sleep disturbances, sudden crying, tremors, vomiting, diarrhea, and low weight gain.
- Dilation of blood vessels (vasodilation).
- Slow and shallow breathing (respiratory depression).
- Difficulty swallowing (dysphagia), flatulence, bowel obstruction (ileus).
- Increased liver enzymes.
- Dryness of the skin.
- urinary retention.
- erectile dysfunction.
- Chills, withdrawal syndrome, discomfort, swelling of the hands, ankles and feet (edema, peripheral edema), drug addiction (tolerance).
- thirst.
- Delay in heart rate (Bradycardia).
- low blood pressure (hypotension), dizziness on standing (orthostatic hypotension).
- Itchy rash.
- Severe allergic reaction (anaphylactic reaction).
- aggressiveness.
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- Never take oxycodone in the following cases:
- in children under 18 years of age.
- If you are allergic to oxycodone hydrochloride or any of the other ingredients of this medication.
- If you suffer from a serious lung disease associated with narrowing of the airways (chronic obstructive or BPCO bronchopneumopathy).
- If you suffer from severe bronchial asthma.
- If your breathing is unable to bring enough oxygen into the blood and eliminate carbon dioxide from your body (severe respiratory depression with hypoxia).
- If the carbon dioxide in your blood is too high.
- If you suffer from intestinal dysfunction with intestinal occlusion (paralytic ileus).
- If you suffer from heart problems after chronic pulmonary insufficiency (pulmonary heart).
- If you are breastfeeding.
- If you are being treated with morphine medications such as buprenorphine, nalbuphine, pentazocine (substances with properties similar to those of oxycodone) and with medications containing naltrexone, nalmefene and sodium oxybate.